Family Guy

The animated series has welcomed - and mocked - many of rock's biggest stars during its long television run.

Some people just can't handle the power of Van Halen.

Leave it to Family Guy to make room for a Rush gag in a tribute to classic literature.

The latest update to 'Family Guy: The Quest for Stuff' works Gene Simmons and Paul Stanley into a holiday-themed adventure.

Steve Vai was taught by Joe Satriani, played in Frank Zappa's band and calls rock legends like Led Zeppelin and Queen major influences. When the Big 100.3 in Washington D.C. asked Vai who he'd like to collaborate with, the guitarist named a major player ... in animation.